Sabalenka is currently +285 to repeat as champion, second only to Iga Swiatek at +240. Sinner, meanwhile is favored to repeat at +110, slightly ahead of rival Carlos Alcaraz at +175. With some of those odds in mind, let's take a look at some of the best betting options to consider in both the men's and women's tournaments this year in New York.

Carlos Alcaraz won the Cincinnati Open on Monday after Jannik Sinner was forced to retire due to illness. Alcaraz was already up big on Sinner, the World No. 1, when he had to retire. Sinner told the crowd that he hoped to play after feeling bad overnight, but he couldn't make it work.

The second spot in the 2025 Cincinnati Open men’s singles final is on the line Saturday night, as No. 2 Carlos Alcaraz battles No. 3 Alexander Zverev.