It's a difficult schedule as our Lions insider Dave Birkett notes, as he gives his game-by-game picks and preseason predictions here. Start the day smarter. Get all the news you need in your inbox each morning.

Detroit's 2025 slate will be a grind, with 11 games against teams that made the playoffs last season. The team will play eight home games and nine on the road, and will be battle-tested throughout the year for what it hopes is another postseason run.

The 2025 NFL schedule release blows out the doors on Wednesday evening. While we already know the Detroit Lions home and road opponents for the coming season, the sequence and schedule of games haven't been unveiled.

The Detroit Lions' 2025 regular season schedule will be released on May 14th at 8 p.m. ET on NFL Network and the NFL's digital platforms. The Lions have the third-toughest schedule in the NFL according to a betting expert.

The Detroit Lions will reportedly open their 2025 NFL season on the road with a matchup against their NFC North rival, the Green Bay Packers.

The Lions and the Packers both made the playoffs in 2024, and each is considered a strong contender for the NFC North crown in 2025. But recent history has been on the side of Detroit, as the Lions have not only won the division title in back-to-back seasons,