A U.S. appeals court ruled on Wednesday that a federal law that bars illegal drug users from owning guns potentially could be deemed unconstitutional when it is applied to medical marijuana users.

Siding with medical-marijuana patients in a Florida case, an appeals court on Wednesday found that federal restrictions barring medical-marijuana patients from buying and using guns appears to run afoul of the Second Amendment.

A federal appeals court has handed medical marijuana patients a major victory, ruling that the government hasn’t shown that banning them from owning guns lines up with America’s long-standing traditions of firearm regulation.