Kickoff is set for 4:25 p.m. ET from Caesars Superdome in New Orleans. According to the latest NFL odds, the Saints are favored by 1.5 points, while the over/under for total points scored is 41. The Saints are -128 money line favorites (risk $128 to win $100), while the Falcons are +109 underdogs.

Looking for an anytime touchdown scorer for Sunday’s action? The SI Betting team has you covered, as NFL betting insider Iain MacMillan and managing editor Pete

The Patriots look to move to a 10-2 record today against the struggling Bengals. Our Patriots vs. Bengals expert predictions highlight the best betting picks for the AFC clash.

The Pittsburgh Steelers and Chicago Bears are two of the NFL’s more surprising teams. Both teams lead their respective divisions. However, there are still plenty of doubters for both teams, which makes this a compelling and potentially revealing head-to-head matchup.

The Seattle Seahawks, led by quarterback Sam Darnold, face the Tennessee Titans, led by quarterback Cam Ward, on Sunday, Nov. 23, 2025 at Nissan Stadium in Nashville, Tenn.

Week 12 of the 2025 NFL season kicked off Thursday with the Houston Texans defeating the Buffalo Bills. But there's still plenty of action to come this weekend.

FC Barcelona want Harry Kane — as far as the Spanish newspapers are concerned (Mundo Deportivo via Barca Blaugranes ). This may be an expression of delusion on their part, or perhaps an elaborate act of performance art for club members. It’s hard to tell when MD is involved.

Quarterbacks and one particularly prominent running back are in the injury spotlight in Week 12, although we also have several big-name wide receivers whose availability bears monitoring leading up to the first wave of games.