New York, NY - Doubts about the effectiveness of the new renin inhibitor antihypertensive aliskiren (Tektura, Novartis) have been voiced in a somewhat controversial review article in the May 2007 ...

San Diego, CA - Cardiorenal results from the multicenter Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE) trial, testing aliskiren (Tekturna, Novartis Pharmaceuticals) as an ...

Novartis announced today the early termination of the ALTITUDE trial, which was testing the effect of the direct renin inhibitor aliskiren (Rasilez, Tekturna) in type 2 diabetics at high risk for ...

Discover comprehensive details about Aliskiren, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it. The updated prescription ...

Last December the once-promising direct renin inhibitor aliskiren (Rasilez, Tekturna) suffered a fatal setback with the early termination of the ALTITUDE trial. The trial was stopped when the Data ...

Ischemic heart disease including myocardial infarction (MI) is the major cause of death in industrial countries. 1, 2 MI frequently causes left ventricular dilatation associated with cardiomyocyte ...

The first evidence of the existence of renin was presented by Tigerstedt over 100 years ago. However, the importance of renin and the renin–angiotensin system (RAS) in the pathogenesis of ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Patients with type 2 diabetes and chronic kidney disease ...

G_hyperkalemia_web Adding aliskiren to losartan in patients with nondiabetic chronic kidney disease does not result in a greater renal protection and increases their risk of hyperkalemia, a study ...

AMSTERDAM, The Netherlands—Aliskiren, a renin inhibitor, does nothing to stall progression of atherosclerosis in prehypertensive patients with coronary artery disease, according to results from the ...

The case-control analysis found no significant difference in the angioedema risk for aliskiren monotherapy and fixed-dose combination compared to BBs with adjusted odds ratio of 0.99 (95% CI, ...

Learn everything you need to know about Aliskiren and Hydrochlorothiazide-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it. Get up-to-date information on side effects, ...