Researchers demonstrated how amino acids could spontaneously attach to RNA under early Earth-like conditions using thioesters, providing a long-sought clue to the origins of protein synthesis. This ...
Researchers are building out the repertoire of chemical reactions, using light. They report a method using photobiocatalysis to produce non-canonical (not naturally occurring) amino acids that are ...
One of life's many mysteries is how it ended up choosing only a set of 20 amino acids to build proteins for its wide catalog of organisms, from single-celled bacteria to behemoth whales. From a ...
Nearly all known life builds proteins from the same alphabet of 20 canonical amino acids. Strung together in different orders, those building blocks form the proteins that make cells work. In a new ...
Professor Jian Wang's research group at Tsinghua University reported a photocatalyzed/nitrogen heterocyclic carbene-catalyzed asymmetric radical α-alkoxycarbonylation reaction of amines. Using ...
Pyruvate kinase M2 (PKM2) occupies a central role in cancer metabolism, catalysing the final and rate-limiting step of glycolysis by converting phosphoenolpyruvate to pyruvate. It exists in ...
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