The androgen receptor is a key transcriptional factor for the proper sex development -- especially in males -- and the physiological balance of all the tissues that express this receptor. The androgen ...
Prostate cancer is the most-commonly diagnosed malignancy and the second leading cause of cancer death among men in the United States. In its ever-indelicate world, the stubborn disease can continue ...
The development of effective cancer therapeutics depends largely on availability of experimental models that reflect the biology and pharmacological susceptibility of the tumor type they represent.