DNA methylation is one epigenetic modification of the genome essential for mammalian embryonic development (Li et al., 1992a), X-chromosome inactivation (Jaenisch et al., 1998), genomic imprinting ...
The inappropriate expression of TGFα in growth arrest contributes to malignant progression in human colon carcinoma cells. Early stage, non-progressed colon tumor cells show a down-regulation of TGFα ...