Accuracy and Surgical Impact of Magnetic Resonance Imaging in Breast Cancer Staging: Systematic Review and Meta-Analysis in Detection of Multifocal and Multicentric Cancer Among the most promising ...

DURHAM, N.C. -- A breast cancer gene's newly discovered role in repairing damaged DNA may help explain why women who inherit a mutated copy of the gene are at increased risk for developing both breast ...

Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression. A new study led by The ...

T cell lineage maturation is a highly regulated process requiring intact DNA repair capacity 1,2. BRCA1 (breast cancer 1, early onset) is a tumor suppressor that probably has a DNA repair function.

A new study funded by Cancer Research UK has mapped out some of the earliest changes that occur in seemingly healthy breast tissue long before any tumors appear, which could have significant ...

A pathway helping the breast cancer protein BRCA1 repair damaged DNA has been identified by University of Queensland researchers in a study that will inform future targeted therapies. Professor Robert ...

PARP inhibitors (PARPi) leverage synthetic lethality in BRCA-deficient cancers, yet intrinsic resistance limits therapeutic benefit. Through functional proteomics, this study uncovers that PARPi ...

The full name of the BRCA1 gene is “breast cancer 1, early onset,” and it codes for a tumor suppressor protein. Tumor suppressor proteins help repair DNA that has become damaged in order to ensure the ...

Navigating Hormone Therapy Choices After OophorectomyFor women carrying BRCA1 or BRCA2 pathogenic variants, the decision to ...