It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age too, and some change in ways that weaken the very structure of our bones.

Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin. These proteoglycans ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

Animal bodies are hierarchically organised from molecules and cells through tissues, organs and whole systems. Cellular architecture—membranes, cytoskeletons and extracellular matrices—provides ...

The From Labs to Lives Blog connects everyday topics with UC Davis research. Each post is reviewed by our experts, ensuring you always get useful information you can trust. Because we can’t see them, ...

As we age, the health of our bones becomes increasingly important. Osteoporosis, a condition characterized by weakened bones, affects millions, leading to fractures and reduced quality of life. Among ...

Discover which makes your bones stronger as you age.