Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Cellular phase separation may play a previously underappreciated role in regulating kinase activity, offering therapeutic ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Purinergic signaling, mediated by extracellular nucleotides such as ATP and UTP, has been increasingly studied for its role in regulating cellular communication. A new review by researchers in ...

A team at Huntsman Cancer Institute at the University of Utah (the U) has uncovered a previously unrecognized molecular mechanism by which cells send signals to one another-insight that could help ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...

• BTK inhibitors work by targeting and blocking the BTK enzyme, which is crucial for the survival and growth of cancerous B-cells in mantle cell lymphoma (MCL). This cuts off the cancer cell’s support ...

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are encouraging. But for a subset, remission is not the end of the story. Roughly 30% ...