The β-lactam scaffold remains the cornerstone of many clinically vital antibiotics, including penicillins, cephalosporins and carbapenems. Central to their synthesis is the construction of a strained ...

Surgical antimicrobial prophylaxis using non-beta‑lactams administered before major surgery was independently associated with a significantly higher risk for surgical site infection than conventional ...

Please provide your email address to receive an email when new articles are posted on . I routinely see prescribers avoid prescribing cephalosporin antibiotics for patients with a penicillin allergy.

With the FDA tightening its guidance around the production of nonbacterial beta-lactam drugs, Swedish CDMO Recipharm is touting new efforts to stay in compliance—and a new partnership. Juggling a mix ...

In children with low-risk allergies to oral cephalosporins, direct challenges showed remarkable safety, with 97.5% of challenges being asymptomatic and no cases requiring epinephrine. Overall, 68% of ...