An experimental gene-editing therapy that aims to lower bad cholesterol for the long-term after a single infusion is off to a ...

Cholesterol biosynthesis disorders encompass a group of inborn errors and pharmacologically induced perturbations affecting the multistep metabolic cascade that generates cholesterol from acetyl-CoA.

Since then, many scientists, including Lu, who now leads his own research group at Western University, have shown that PIN1 is overexpressed in different types of cancer and regulates many oncogenes ...

Kinases that shuttle cholesterol within tumor cells help fuel growth. Blocking these enzymes may starve cancer cells, ...

Researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice. Like all cancers, bladder ...

A research team from the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has made a breakthrough in gastric cancer research, revealing how the "second brain"—nerves in the digestive ...