Regulation of nuclear receptor activity is the focus of numerous ongoing studies to develop novel therapies for the treatment of hormone-related cancer. Although cyclin D1 functions to control the ...
As the incidence of type 2 diabetes increases, new treatments are clearly needed. Many hormones and drugs that control metabolic pathways function as agonists or antagonists of nuclear receptors, ...
The C-terminal binding protein 1 (CtBP) is a ubiquitous corepressor linking the recruitment of DNA- and histone-modifying proteins to sequence-specific DNA-binding proteins and facilitating gene ...
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