Preclinical testing has proven that our antibody neutralizes the diphtheria toxin. Our next step is to generate enough of it for a Phase 1 clinical trial in humans that will validate its dosage ...

Toxin-producing Corynebac­terium diphtheria usually causes two types of diseases, respiratory diphtheria which affects the upper throat, and skin diphtheria which affect the skin.

Diphtheria is mediated by a toxin produced by the causative organism Corynebacterium diphtheriae, ... Diphtheria is a vaccine-preventable disease affecting mainly children.

The symptoms of diphtheria are caused by a toxin that is released by the bacteria that cause the condition. Two types of bacteria can cause diphtheria and these include: Corynebacterium ...

Diphtheria is an extremely contagious disease with similar symptoms to the common cold. ... According to a 2019 article, some variants of this bacterium produce a toxin called an exotoxin.

In most cases, the bacteria cause acute infections, driven by the diphtheria toxin—the key target of the vaccine. However, non-toxigenic C. diphtheria can also cause disease, ...

Diphtheria was first named in 1826, but it has existed for a lot longer. It used to be a major problem in the U.S. until the vaccine was developed and put into use in the 1920s.

All the latest science news on diphtheria toxin from Phys.org. Find the latest news, advancements, and breakthroughs.

Diphtheria - a relatively easily-preventable infection - is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international ...

In 1901, for example, Emil von Behring was rewarded for his discovery that serum containing antibodies to the diphtheria toxin could be used to treat the disease. Against the grain.