A new study provides important insight into the mechanisms of a muscle wasting disorder that interferes with treatment for cancer and has a negative impact on patient survival. The research, published ...
Telomeres shorten without cell division in a mouse model of Duchenne muscular dystrophy, new research shows. Subsequent DNA damage responses and mitochondrial dysfunction are likely cause of heart ...
Since utrophin compensates for lack of dystrophin in mdx mice, which results in a milder phenotype of muscular dystrophy compared to humans, the mdx/utrn-/- mouse has been developed to mimic early ...
Sarepta Therapeutics and University of Western Australia Announce Exclusive Worldwide Licensing Agreement for Exon-Skipping Program in Duchenne Muscular Dystrophy Deal Enables Development of New ...
Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that results from mutations in the DMD gene. Gene therapies for DMD change genetic material in a person’s body to treat this condition.
A class of drugs used to treat erectile dysfunction could also treat blood-flow problems related to Duchenne muscular dystrophy--a bright spot in a disease field marked by repeated clinical setbacks.