Researchers at MIT found that roughly a quarter to a third of all synapses in the adult mouse cortex are functionally silent, ...

A researcher has developed a new model that provides a holistic view on how our brain manages to learn quickly and forms stable, long-lasting memories. Their study sheds light on the crucial role of ...

The way the brain develops can shape us throughout our lives, so neuroscientists are intensely curious about how it happens. A new study by researchers in The Picower Institute for Learning and Memory ...

BIN1, a late-onset Alzheimer’s disease (LOAD) genetic risk factor, is involved in many cellular phenomena, including vesicular trafficking and tau production. Now, in the August 26 Cell Reports, ...

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has demonstrated that brain wiring requires the control of local protein synthesis at the ...

Astrocytes are notoriously two-faced—calmly coddling neurons one minute, then ruthlessly consuming their synapses the next. Why these dramatic mood swings? Blame the EphA4 receptor, according to a ...

Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...

Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...

One of society’s greatest medical challenges is to understand and develop effective treatments for disorders of intellectual disability (ID). Around 2–3 percent of the global population meet the ...

Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity. Known as inhibitory synapses, these neural connections are rebalanced so that we ...