RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

Researchers from A*STAR’s Genome Institute of Singapore (GIS) have found an innovative approach to sequencing single-cell ribonucleic acid (RNA) to study the roles of RNA structure in individual cells ...

The central dogma of molecular biology showing what is happening in this study. Credit: Julian Chen For the very first time, a study led by Julian Chen and his group in Arizona State University's ...

A research team at Florida State University's Institute of Molecular Biophysics and Department of Chemistry and Biochemistry ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...

The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic, claims a German-Austrian research team led by the Leibniz Institute for Natural ...

An artistic representation of the temperature dependence of the RNA free-energy landscape (FEL) of folding. The authors showed that RNAs undergo a phase transition in the cold and misfold due to the ...

A Northwestern Medicine study has shed light on a critical molecular mechanism underlying amyotrophic lateral sclerosis (ALS) ...