A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

Glycogen serves as an essential energy reserve in the central nervous system, predominantly stored in astrocytes but also synthesised at low levels in neurons. Its synthesis is driven by glycogen ...

In a new study published in Nature Metabolism titled “Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction,” researchers from the Buck ...

A sugar molecule churned out by gut bacteria may be one of the missing triggers behind ALS, and eliminating it in mice reversed the disease’s hallmark symptoms. That is the central finding of a study ...

Mycobacterial species deploy intricate pathways to synthesise and remodel glycogen-like α-glucans and complex polysaccharides that underpin both energy storage and pathogenicity. Intracellular ...

When we eat foods containing sugar, our bodies convert the excess into glycogen, which is mainly stored in the liver and muscles. Scientists have studied glycogen metabolism for centuries. This ...

Researchers discover that glycogen and N-linked glycans accumulate in fibrotic regions of the lung and may be important for therapy development. Ramon Sun, a biochemist at the University of Florida ...

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, ...

Amyotrophic lateral sclerosis strips away the ability to move, speak, and eventually breathe, usually killing within two to ...