The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...
This image shows the replication cycle of HIV/SIV. The virus replicates in the body's own CD4+ T helper cells. In doing so, it introduces its own genetic information into the DNA of the host cell.
On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...
LA JOLLA, Calif., June 26, 2009 – Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce ...
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Study reveals previously unknown role for viral protein integrase in HIV's life cycle
The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.
Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines ...
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