MPR

Gene Therapy Kresladi Approved for Severe Leukocyte Adhesion Deficiency-I

This hematopoietic gene therapy offers a new treatment for children with severe leukocyte adhesion deficiency-I without matched transplant donors.
The American Journal of Managed Care

Study Suggests Genetic Link Between HLA Alleles, MG

Two human leukocyte antigen (HLA) alleles, DRB1*04.04 and DRB1*03, show a significant correlation with myasthenia gravis (MG) prevalence. Northern Europe exhibits the highest prevalence of MG and ...

Rocket Pharmaceuticals Wins FDA Accelerated Approval for KRESLADI Gene Therapy in Severe LAD-I Kids

Rocket Pharmaceuticals (NASDAQ:RCKT) said the U.S. Food and Drug Administration has granted accelerated approval to KRESLADI ...
MedPage Today on MSN

FDA OKs therapy for deadly pediatric immune disorder

Kids with severe LAD-I, caused by ITGB2 mutations, are at risk of life-threatenin ...
European Medical Journal

HLA-B27 Status Shapes Axial Spondyloarthritis Phenotype

An MRI-based cohort study shows HLA-B27–positive axial spondyloarthritis is linked to higher inflammation and distinct ...
Medscape

Allopurinol Skin Reaction Genetics Described in US Patients

A small study tied specific human leukocyte antigen (HLA) class I alleles to a higher risk for allopurinol-induced severe cutaneous adverse reactions (SCARs) in the US. Researchers analyzed 16 ...
Healio

Study finds shared genetic susceptibility of psoriasis, hidradenitis suppurativa

Please provide your email address to receive an email when new articles are posted on . Patients with both psoriasis and hidradenitis suppurativa had the highest overall psoriasis genetic risk score.
The American Journal of Managed Care

Elevated HLA-G Seen in HCC Driven by Viral Infections, Fatty Liver

Elevated HLA-G levels in HCC patients are linked to worse survival, indicating its potential as a prognostic marker. HCC patients with viral hepatitis or steatotic liver disease show significantly ...