We have identified a family in which typical EI developed in an epidemic setting in four male siblings and their father. Three individuals who were HLA-B27+ developed arthritis (Figure). Two nine year ...

Human leukocyte antigen B27 (HLA-B27) positivity was associated with higher odds of non-remission in patients with juvenile idiopathic arthritis (JIA) at 18 years after disease onset, with men showing ...

The HLA-B27 genetic marker is known to be associated with increased risk for various arthropathies, including JIA. Whether the genetic marker's presence has prognostic value has been uncertain. In ...

In patients with spondyloarthritis, onset of common musculoskeletal symptoms such as back pain led to diagnostic delays averaging over 7 years. Onset with extra-musculoskeletal manifestations such as ...

Spondylitis is an umbrella term for a group of chronic arthritis-type diseases affecting the joints of the spine and sacroiliac region. The sacroiliac region includes the pelvis and lower spine.

Spondyloarthritis is a group of inflammatory joint diseases that affect the spine and, in some cases, the peripheral joints of the arms and legs. Some forms of spondyloarthritis may also involve the ...