This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

The boxes along the top and right-hand side of the figure represent potential pathophysiological cellular and end-organ mechanisms that underlie the disability of peripheral arterial disease and ...

Extracorporeal shockwave therapy may be effective for intermittent lower limb claudication in peripheral artery disease (PAD) patients unable to engage in supervised exercise or who experienced little ...

Claudication is muscular pain, cramping, or fatigue that typically occurs during exercise and goes away with rest. Claudication is primarily a symptom of conditions that reduce blood flow in the legs, ...