D-lactate is the stereoisomer of L-lactate that arises primarily through microbial fermentation in the gut and via the glyoxalase pathway in human tissues. Under normal circumstances, low levels of ...

Abstract: Neural tissue requires a great metabolic demand despite negligible intrinsic energy stores. As a result, the central nervous system (CNS) depends upon a continuous influx of metabolic ...

Lactic acid bacteria (LAB) are a diverse group of Gram-positive microorganisms widely exploited for their capacity to ferment carbohydrates into lactic acid stereoisomers. Central to their metabolism ...

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...

Announcing a new article publication in BIO Integration. Pulmonary fibrosis (PF) is a progressive and irreversible ...

A new review reveals how lactate and its derivative lactylation process drive breast cancer progression, opening new therapeutic possibilities. The study demonstrates that lactate—a metabolic ...

This breakthrough enables higher yields of poly(3-hydroxybutyrate-co-lactate) [P(3HB-co-LA)] without disrupting bacterial growth, paving the way for more sustainable bioplastic manufacturing. The ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Last week, I wrote a post about how high-intensity aerobic exercise can stimulate the release of brain-derived neurotrophic factor (BDNF), a protein that's often described as Miracle-Gro for the brain ...