Leptin, a hormone produced chiefly by adipose tissue, plays a central role in coordinating energy balance, immune responses and vascular homeostasis. Beyond its well-characterised functions in ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Leptin, a hormone predominantly secreted by adipose tissue, exerts far-reaching roles in the central nervous system beyond its established function in energy homeostasis. In the brain, leptin ...

They found that in leptin-resistant mice, the levels of two essential amino acids are dysregulated in response to leptin. These two amino acids, methionine and leucine, are known activators of a ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...

Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use. Featured in the February ...

Anil Oza is a general assignment reporter at STAT focused on the NIH and health equity. You can reach him on Signal at aniloza.16. The hormone leptin was discovered 30 years ago to much fanfare.

A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged ...

Typically, when PD is diagnosed, half of the dopaminergic axons and neurons within the substantia nigra pars compacta are already lost. Thus, there is an urgent need to identify early PD markers. The ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

“Up until now, the scientific community thought that leptin acts exclusively in neurons to modulate behavior and body weight,” Horvath said in a press release. “This work is now changing that paradigm ...

SOME PETS WERE RESCUED FROM HOMES. ALL NEW AT FIVE. AND FOR YOUR HEALTH, THE MEDICAL RESEARCHERS AT THE UNIVERSITY OF PITTSBURGH ARE AT IT AGAIN. THEY PUBLISHED RESEARCH LAST WEEK FOCUSING ON A WAY TO ...