Lithium (Li⁺) remains a foundational treatment in psychiatry, particularly for bipolar disorder, manic episodes, and suicide prevention in major depressive ...

Alzheimer’s disease, which represents 60–80% of dementia cases 1, robs people of their memory, cognition and independence. A decade-long period of mild cognitive impairment precedes the onset of ...

Endogenous lithium levels were lower in the prefrontal cortex of people with Alzheimer's and mild cognitive impairment. Lithium depletion in mouse models led to increased amyloid and accelerated ...

Alzheimer’s disease steals memories and devastates lives. Yet despite an abundance of research, the earliest brain changes that trigger this disease still remain unclear, making it challenging to find ...

A new study reveals that brain lithium depletion occurs early in Alzheimer’s and fuels disease progression, while low-dose lithium orotate in mice can protect against memory loss and brain damage, ...

Marissa Russo is a former STAT intern supported by the AAAS Mass Media Science & Engineering Fellowship. A new study finds that the element lithium plays a crucial role in healthy brain function and ...

Tiny amounts of lithium -- a natural metal -- may help protect the brain from Alzheimer's and signs of aging, new research shows. Scientists at Harvard Medical School and Rush University found that ...

Lithium, long prescribed for bipolar disorder and as an adjunct in depression, is essential for brain resilience, and new research suggests that deficiency of the mineral in neural tissue may ...

In a major new finding almost a decade in the making, researchers at Harvard Medical School say they’ve found a key that may unlock many of the mysteries of Alzheimer’s disease and brain aging — the ...

Low doses in mice have can clear up proteins associated with Alzheimer’s disease and restore memory. Human trials are the next step. Lithium has long been a standard treatment in bipolar disorder, but ...