NFL, Cardinals and Jacksonville Jaguars
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The Jaguars are 5-4-1 against the spread, while the Cardinals are 5-5 ATS. Arizona has the 14th-best offense and 21st best defense, while Jacksonville has the 19th-best offense and14th-best defense. The SportsLine model projects one side of the spread has all the value. Jaguars vs. Cardinals score prediction: Jaguars 26, Cardinals 23
The Arizona Cardinals are looking to get back on track when they host the Jacksonville Jaguars on Sunday afternoon. The Cardinals have been outscored 85-44 in t
Ence's Prediction: Jacksonville takes care of business in Arizona.
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Week 12 NFL odds, lines, best bets, predictions: Computer model backing Ravens and Cardinals
The Week 12 NFL odds feature four games with a spread of a field goal or less, while three contests have a double-digit NFL line. Amongst the former are Steelers vs. Bears (-2.5), with Aaron Rodgers' (wrist) listed as questionable,
ARIZONA -- Arizona Cardinals TE Trey McBride was fined $14,491 by the NFL for his first-down celebration in Week 11 against the San Francisco 49ers. McBride's "nose wipe" was considered to be a violent gesture by the league, as the NFL believes the previously popular move has ties to gang activity.
NFL RedZone — an around-the-horn live highlight show demonstrating all the action on NFL Sunday — is back for Week 12 of the 2025 season.
Quarterback Kyler Murray is on injured reserve with a foot injury, running back James Conner is out for the season, running back Trey Benson has missed the past six games and wide receiver Marvin Harrison Jr. will miss his second consecutive game this weekend.
USA TODAY Touchdown Wire on MSN
NFL experts predict Jaguars vs. Cardinals Week 12 winner
After a big win last week against the LA Chargers, the Jaguars improved to 6-4 on the season, and they are currently the seventh seed in the AFC playoff race. The Cardinals find themselves at 3-7 on the year and have won just one of their last eight games after a 2-0 start.
With the loss, according to Tankathon, the Cardinals are in the top 10 of the NFL draft order, moving up one spot over last week. They would have the 10th overall pick in the draft if the season ended today. The Cardinals have the same record as the Falcons and the Bengals but would pick after them if the season ended today.
NFL Sunday Week 12 is here and we asked USA TODAY Sports' staff for their best bets for every NFL game today. Here are their picks and predictions:
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