Intrinsically disordered proteins and complex multidomain proteins are characterized by a dynamic ensemble of conformations that cannot be unequivocally described by traditional static terms of ...
Modeling indicates that secondary structures of RNA in the genes encoding the Nsp4 and Nsp16 proteins of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are different from other ...
Information about the secondary and tertiary structure of proteins is obtained by monitoring molecular vibrations using Raman spectroscopy. Dynamic light scattering or DLS helps in determining the ...
Proteins are made of amino acid chains, or polypeptides. Amino acids have a basic backbone made of an amino group and a carboxyl group, and differ in their side-chains. These polypeptide chains of ...
In protein formulations, native-state unfolding and aggregation holds major significance for both patients and manufacturers. A better understanding of aggregation is therefore required for improve ...