The ribosome, that protein-making machine, relies on other, smaller machines. For example, it works in concert with a mechanism that supplies amino-acid-carrying tRNAs, including tRNAs that require ...

The fruit fly lacks the tRNA nuclear export receptor Exportin-t, which only exports end-processed tRNAs to the cytoplasm to ensure the completion of the processing steps in the nucleus. The related ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Researchers have identified a novel brain disorder that is neurodegenerative, but so early onset that it disrupts development, leading to disturbances in the formation and function of hindbrain ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...