The following protocol describes the selective cross-coupling of an amine with an aryl halide using a Pd-based catalyst to provide the corresponding N-arylated amine. This general procedure for C–N ...

It’s hard to improve on a classic. But Richard Y. Liu was eager to take on that challenge. Cross-coupling reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, are some of the ...

A University of Illinois at Urbana-Champaign research team has discovered a way to produce a special class of molecule that could open the door for new drugs to treat currently untreatable diseases.