Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells. RNA molecules are real all-rounders. They transfer the genetic information from ...

Ribozymes are RNA molecules that are capable of catalyzing a chemical reaction. Ribozymes occur naturally inside cells where they play an essential role in the ribosome, joining amino acids together ...

In new research published in the journal Angewandte Chemie, scientists applied a high throughput methodology to study the ribozyme in an innovative way. While work in this area has typically used ...

RNA molecules are real all-rounders. They transfer the genetic information from the DNA in the cell. They regulate the activity of genes. And some of them have a catalytic effect: just like enzymes, ...

In the present study, as an alternative strategy for survivin inhibition, we designed two hammerhead ribozymes against human survivin mRNA and examined the function of the ribozymes and the effects of ...

A study finds that an RNA enzyme, or ribozyme, can evolve to produce complex RNAs efficiently but at the cost of synthesis accuracy. Key to the development of RNA-based life, which is thought to have ...

Enzymes enable biochemical reactions that would otherwise not take place on their own. In nature, it is mostly proteins that function as enzymes. However, other molecules can also perform enzymatic ...

Although ribozymes capable of performing a wide range of reactions have been evolved in the lab, only a handful of classes of these RNA-based catalysts are found in nature. Now, a new type of ribozyme ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

We investigated whether a continuous transcript is necessary for co-transcriptional pre-mRNA processing. Cutting an intron with the fast-cleaving hepatitis δ ribozyme, but not the slower hammerhead, ...

Researchers have developed the first cross-chiral biocatalyst—a right-handed (d) RNA enzyme that catalyzes the linkage of left-handed (l) RNA nucleotides into l-RNA chains. No other RNA or protein ...

RNA molecules are real all-rounders. They transfer the genetic information from the DNA in the cell. They regulate the activity of genes. And some of them have a catalytic effect: just like enzymes, ...