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49ers, Panthers and San Francisco

Carolina Panthers vs. San Francisco 49ers Week 12 preview

The Panthers return to primetime for the first time in two years, and how fitting it is against Christian McCaffery in his first game facing his former team since he was traded.

NFL · 2h

Panthers vs. 49ers: Three must-know storylines for Monday's Week 12 prime-time game

Niners Wire on MSN · 18h

49ers vs. Panthers injury report: San Francisco rules two out for MNF

49ers void Brandon Aiyuk's 2026 guarantees

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Brandon Aiyuk may have played his final game with the 49ers

"It’s now likely that he (Aiyuk) has played his last game with the franchise, according to numerous sources briefed on the matter, who spoke on the condition of anonymity to discuss a sensitive situat...

· 12h · on MSN

San Francisco 49ers void Brandon Aiyuk's contract guarantees for 2026

· 1d · on MSN

Brandon Aiyuk has reportedly played his last game for the 49ers

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When Could Brandon Aiyuk Be Released by 49ers? Latest Rumors on WR's Contract

Signs are pointing to the San Francisco 49ers releasing wide receiver Brandon Aiyuk at the end of the 2025 season, according to Dianna Russini and Michael Silver of The Athletic.

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49ers Insider Paints Grim Picture for Brandon Aiyuk Return in 2025

· 11h

Amid acrimony, Kyle Shanahan ‘holding out hope' Brandon Aiyuk plays for 49ers again

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NFL teams that benefit most from Brandon Aiyuk's impending release

49ers are now free to clear up about $85 million of salary-cap space owed to Brandon Aiyuk.

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Will Brandon Aiyuk Be Released? 'Stunning Divorce' with 49ers Reportedly Possible

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49ers and star wide receiver Brandon Aiyuk preparing to part ways, report says

What channel is Cardinals vs 49ers NFL game today? Start time, schedule, where to watch, stream

The NFL season continues in Week 11 when the San Francisco 49ers host the Arizona Cardinals on Sunday. Start time, how to watch, streaming and NFL schedule.

49ers vs. Panthers 2025 Prediction, Odds, Picks - Nov 24

Preview the Week 12 matchup between the San Francisco 49ers and Carolina Panthers with predictions, odds, over/under, spread, betting lines and more.

Niners Wire on MSN

49ers vs. Cardinals highlights: San Francisco blows out NFC West rival in big game

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are the highlights.

San Francisco 49ers

Saleh, Kubiak Highlight Player Development and Game-Plan Focus

San Francisco 49ers defensive coordinator Robert Saleh and offensive coordinator Klay Kubiak detailed the team's progress in the run game and discussed the mindset needed to carry momentum into their primetime matchup.

USA TODAY Touchdown Wire on MSN

George Kittle 'can't get over' effort from 49ers rookie defender through 11 games

San Francisco 49ers tight end George Kittle has been thoroughly impressed by what he's seen from defensive lineman Alfred Collins so far this year.

3don MSN

49ers Sign New Kicker, Release WR After Eddie Pineiro Injury News

The 49ers' kicking situation is in flux after Eddy Pineiro's injury, so they addressed it by signing veteran Matt Gay to their practice squad Wednesday.

49ers' Kyle Shanahan questioned about Christian McCaffrey's late-game usage in blowout win

San Francisco 49ers head coach Kyle Shanahan said he had big comebacks in mind when he kept Christian McCaffrey on the field with his team leading by 19 late in Sunday's game.