Treating inflammatory or autoimmune disorders in which the immune system overreacts and starts attacking the body can involve shutting down the whole immune system, and this may increase the risk of ...

Balancing the immune system is a delicate act. If it’s too weak, infections and cancer can take hold; if it’s too strong, autoimmune diseases or transplant rejection can occur. Researchers have ...

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune ...

Engineered cell products such as CAR T cells have demonstrated considerable therapeutic potential. Two studies in Science report new avenues to expand the applications of synthetic cell therapies – ...

Cancer immunotherapy has already transformed treatment for some patients, yet too often the body’s defenders stall out before ...

Immune cells that are designed to soothe could improve treatment for organ transplants, type 1 diabetes and other autoimmune conditions. When the immune system overreacts and starts attacking the body ...

Immune checkpoint inhibitors (ICIs), including antibodies against the programmed cell death protein 1/ligand 1 (PD-1/L1) ...