Activating the cell surface receptor TREM2 rallies microglia to clear amyloid plaques. Can activating a kinase downstream of TREM2 do the same? Two groups of scientists say yes. In the October 26 Cell ...
The prominent role of the BCR signaling in promoting B-CLL cell survival has prompted new therapeutic strategies targeted to signalosome elements. In particular, the most advanced BCR-signaling ...
Agios obtains exclusive global rights to novel, late-stage, next-generation, oral SYK inhibitor ; Agreement diversifies Agios’ rare hematology portfolio with expansion into immu ...
Scientists have attempted to bolster microglia in the Alzheimer’s brain by switching on TREM2 signaling, but so far, these efforts have met with little success. Might it work better to bypass TREM2 by ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results