As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells—which have lost their cancer-fighting oomph—consume this lactic acid, ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...

SAN FRANCISCO -- The response rate in metastatic gastroesophageal cancer improved by a relative 50% when patients received experimental activated T cells in addition to standard therapy, according to ...

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Newly reported research by scientists at the University of Pittsburgh and UPMC Hillman ...

(MEMPHIS, Tenn. – August 20, 2024) Scientists at St. Jude Children’s Research Hospital and Washington University School of Medicine have discovered why the flu vaccine can perform poorly. They found ...

Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...