One of the biggest fight cards of 2025 has finally arrived. Check out these in-depth UFC 319: Du Plessis vs. Chimaev predictions and betting breakdowns.

The main card begins at 10 p.m. ET and is headlined by middleweight champion Dricus du Plessis defending against the undefeated Khamzat Chimaev. Fans can purchase the event for $79.99 on ESPN+ PPV. The main event walkouts are expected to take place around 12-12:30 a.m. ET.

The UFC is in one of the world’s most legendary cities with the middleweight title on the line at the top of the bill. UFC 319 (pay-per-view, ESPN, ESPN+) takes place Saturday at United Center in Chicago, and it’s the promotion’s first visit there in more than six years.