How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Messenger RNA (mRNA) technology came of age during COVID-19 with several vaccines and therapeutics coming to market. However, since the height of the pandemic, the flow of new mRNA-based products has ...

Unlocking the potential of mRNA technology is helping revolutionize medicine and biotechnology. Solid-phase in vitro transcription enables scalability and automation, helping make it a valuable tool ...

Cell-to-cell communication is essential throughout all forms and stages of life, and many communication mechanisms are well studied. However, over the past few years, scientists have found increasing ...

The discovery of chemical modifications to overcome mRNA’s instability and immunotoxicity have enabled mRNA therapeutics to evolve dramatically, reaching clinical trials and the forefront of modern ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...

Naked mRNA administration in the testes rescues sperm function, demonstrating a potential therapeutic approach for genetic male infertility.

The United States may be losing its edge in mRNA technology­­. The technology, which powered life-saving COVID-19 vaccines and is now rocketing new cancer therapeutics forward, will soon undergo a ...