On Sunday, the 49ers breathed a sigh of relief after McCaffrey showed no indication of discomfort in the 17-13 victory over the Seattle Seahawks. He carried the ball 22 times for 69 yards and added nine receptions for 73 yards through the air.

Most San Francisco 49ers fans would be forgiven for feeling deja vu with star running back Christian McCaffrey’s latest surprise injury, which only popped up on Thursday. But as Sunday’s kickoff against Seattle nears, the reports from NFL insiders are showing McCaffrey expects to play.

ESPN's Mina Kimes and Dan Orlovsky are concerned about the San Francisco 49ers' offense without George Kittle.

If Brock Purdy is your fantasy football starting quarterback and you don't have a backup, options that are available on waivers in more than half of ESPN leagues include: Lawrence has long-term upside this season. He'd be the preference to pick up, for sure. As long as CMC is healthy, he's in your lineup, no questions asked.

Opponents play the 49ers differently when accounting for McCaffrey’s versatility as a runner and receiver, with “the defense not knowing if he’s going to go out for a pass and the element that brings to them and their scheme,” Brock Purdy said ...

In Week 2, the New York Giants and Darius Slayton play the Dallas Cowboys at AT&T Stadium in Arlington, Texas. Kickoff is set for 1 p.m. ET on Sunday. Slayton appears on the injury report this week (limited participation in practice,