Improvements in medical therapy, carotid-artery stenting, and carotid endarterectomy call into question the preferred ...

Explore the current issue of The New England Journal of Medicine (Vol. 393 No. 20).

A 26-year-old woman was referred to the pulmonary hypertension clinic with a 6-month history of exertional dyspnea and hoarseness. Vocal-fold paralysis was seen on laryngoscopy (shown in a video).

A 62-year-old man with hypercapnic respiratory failure was intubated, and a propofol infusion was initiated. Five days after admission, his urine became green.

The Nova food-classification system has advanced efforts to address modern diets of highly processed foods. But it’s unclear whether it can be codified at a national level to support public health.

Personalized therapies hold tremendous promise but challenge traditional models of drug and biologic development. The FDA outlines a path to market entry for products where a randomized trial is no ...

In this international, randomized trial, we assigned critically ill adults who were undergoing invasive ventilation to receive intravenous pantoprazole (at a dose of 40 mg daily) or matching placebo.

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

Competition is vital to the success of Medicare Advantage but is limited. As the program grows rapidly under favorable payment policy, a reformed traditional Medicare could provide valuable competi ...

The Affordable Care Act (ACA) was signed into law 10 years ago. This first of two Health Policy Reports reviewing the challenges and successes of the law focuses on the provisions of the law that ...

State Medicaid agencies can now apply to participate in a new model that supports voluntary, outcomes-based agreements between Medicaid programs and manufacturers of gene therapies for sickle cell ...

No medications are currently approved for the treatment of nonmonogenic, nonsyndromic obesity in children younger than 12 years of age. Although the use of liraglutide has been shown to induce weight ...