A patient arriving in A&E or another clinical setting, with suspected or known infection and the risk of sepsis, requires immediate action. Antibiotic admission more than one hour after suspected ...

Sepsis is a critical global healthcare challenge, marked by complex and rapidly evolving symptoms, which can escalate with alarming speed leading to multi-organ failure. This leaves only a narrow ...

The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

The UK is a recognised powerhouse for genomic science and medicine. Genomics England’s 100,000 Genomes Project is the largest sequencing project of its kind in the world and, building on these ...

Polygenic scores aim to measure the cumulative effect of multiple genetic variants to make predictions about a person’s health. The most likely areas of potential use are in risk prediction, including ...

On Friday the High Court ruled on the case of ABC v St George’s NHS Trust (and other NHS defendants). This is a significant decision with implications for a wide range of healthcare professionals ...

We are getting closer to a world where the debilitating pain and complications of sickle cell disease are a thing of the past. For the 17,500 people in the UK living with this genetic condition, this ...

The European Health Data Space Regulation has arrived but will its mandatory sharing requirement be its tour de force or Achilles’ heel? The Regulation amounts to an ambitious and laudable step ...

A recent consultation by the UK Medicines and Healthcare products Regulatory Agency (MHRA) indicates a welcome new direction for public and patient involvement (PPI). The MHRA proposed new five-year ...