The agent specifically binds to IL-2 receptors on the cell surface, causing diphtheria toxin fragments that have entered cells to inhibit protein synthesis.

Lymphir – a recombinant fusion protein that combines an IL-2 binding domain with diphtheria toxin fragments, designed to bind to and kill leukaemic cells – was turned down by the FDA a year ...

Lieve Van Mellaert; Mohammad Shahrooei; Dorien Hofmans; Johan Van Eldere Disclosures Expert Rev Vaccines. 2012;11 (3):319-334.

The National Orientation Agency (NOA) has commenced a campaign on the causes and prevention of diphtheria in Ebonyi ...

The catalytic domain of diphtheria toxin (DT) is translocated across endosomal membranes by the T-domain (DTT) in response to acidification. Understanding the energetics of translocation, besides ...

The frequency and severity of human infections associated with Corynebacterium ulcerans appear to be increasing in different countries. Here, we describe the first C. ulcerans strain producing a ...

Edo State Director of Public Health, Ministry of Health, Dr. Stephenson Ojeifo has commended the Institute of Child Health, ...

Suspected cases of diphtheria have surged in Edo State amid fears of a dearth of vaccines across the state. It was gathered that the University of Benin Teaching Hospital is overwhelmed with ...

Suspected cases of diphtheria have increased in Edo State amid fears of dearth of vaccines. It was gathered that the University of Benin Teaching Hospital (UBTH) is overwhelmed with patients with ...

Edo State is witnessing a rise in suspected diphtheria cases, raising alarm over an apparent shortage of vaccines to contain the spread. Reports indicate that the University of Benin Teaching ...

UNICEF has recommended regular health checks on incoming passengers at the Sam Mbakwe Airport, Owerri, Imo State as part of measures to check the spread of ...