As age increases, the functions of tissues and organs in the body gradually decline. Due to this decline in organ function, drug absorption, distribution, metabolism and excretion (ADME processes) in ...

THE effects of anticholinergic drugs on gastric function have usually been measured by radiologic studies to determine decrease in motility and tone, or by intubation technics to determine the ...

Most of the enzymes involved in drug metabolism are present in the liver. This means the liver plays a key role in drug metabolism. Drug metabolism occurs when the body chemically alters drugs so it ...

A research team led by Kobe University Graduate School of Medicine's Professor OGAWA Wataru (the Division of Diabetes and Endocrinology) and Project Associate Professor NOGAMI Munenobu (the Department ...

Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

When a drug is absorbed and enters the systemic circulation, it is naturally distributed throughout the fluid and tissues in the body. Drug distribution is a subject that is covered in a branch of ...