High-density lipoproteins (HDL), also known as "good cholesterol," remove excess cholesterol from the body's tissues and ...

They derive their energy from differences in the concentration of hydrogen ions across some of these membranes ...

A protein historian and evolutionary biochemist found that a protein sequence present across all known life didn’t form as ...

ATP has many functions in the body, including neurotransmission, DNA and RNA synthesis, intracellular signaling, and muscle contraction. It can also be used clinically in pain management, anesthesia, ...

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was ...

Abstract: Endothelial cells (ECs) release ATP in response to shear stress, a mechanical force generated by blood flow, and the ATP released modulates EC functions through activation of purinoceptors.

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The mechanism(s) by ...

This valuable manuscript describes ATP5I, a subunit of F1Fo-ATP synthase, as a key target of medicinal biguanides, however, it provides incomplete evidence of a direct interaction between ATP5I and ...

As millions of Americans prepare to hit the road for holiday travel, many U.S. adults feel that driving in their area has become more dangerous than it was before the coronavirus pandemic. Most see ...

As a diehard enthusiast of video games, Ediz Guner has been attentively following the ebbs and flows of the gaming industry for a long period of time. This, coupled with his hobby of extensively ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. While mechanisms controlling uncoupling ...