Kyle Shanahan said Fred Warner will not come off injured reserve this week, ruling him out for Saturday's game in Seattle, but he said he was encouraged that the NFC title game timeline remains in play.

On the other side of the matchup, the 49ers did not activate linebacker Fred Warner from injured reserve. Warner has been sidelined since Week 6 after dislocating his ankle. The 49ers still hope to get him back next week if the team advances to the NFC championship game.

The indications from the 49ers have been that linebacker Fred Warner will not play against the Seahawks on Saturday, but Warner isn't ready to rule anything out yet.

As the NFL divisional round approaches, injuries are playing a major role in shaping each matchup. Several key starters and important depth players for the Saturday match-up are either sidelined or fighting through lingering issues.