In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new ...

This important study fills a gap in our knowledge of the evolution of GPCRs in holozoans, as well as the phylogeny of associated signaling pathway components such as G proteins, GRKs, and RIC8 ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. In this manuscript, ...

State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, ...

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing seven new Research Units. This was decided by the DFG Joint Committee on the recommendation of the Senate. The new ...

Abstract: Molecular communication (MC) is a bio-inspired communication paradigm that utilizes molecules to transfer information and offers a robust framework for understanding biological signaling ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. In response to extracellular ligands, G protein-coupled receptors (GPCRs) undergo ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Photodynamic therapy (PDT) resistance limits ...

Gut Microbiota in Immuno-Oncology: A Practical Guide for Medical Oncologists With a Focus on Antibiotics Stewardship Triple-negative breast cancer (TNBC) was first described as a distinct disease ...

As a neuromodulator, norepinephrine is a powerful force in the brain. We all know it orchestrates rapid changes in behavior such as the fight-or-flight response. Fewer people know that astrocytes ...

Collaboration combines Novo Nordisk’s scientific leadership in obesity and cardiometabolic diseases with Septerna’s expertise in G protein-coupled receptor (GPCR) drug discovery Goal is to develop ...

From dwarfism to overgrowth, scientists unravel the complex genetic blueprint that determines how tall—or short—we become. Review: The genetic basis of human height. Image Credit: XiXinXing / ...