Ismael "El Mayo" Zambada is accused of ordering torture, plotting murders and flooding the U.S. with cocaine, heroin and other illicit drugs.

Sheinbaum’s remarks come in response to the US unveiling a ‘bold bilateral initiative’ to combat drug trafficking.

Despite many arguing the border crisis is over because illegal entries at the southwest border have dropped to their lowest level in recorded history, border-related and cartel crime is flourishing throughout the U.

MEXICO CITY (AP) — Hours after the U.S. Drug Enforcement Administration announced “a major new initiative” for United States and Mexico collaboration targeting gatekeepers who control illicit trafficking routes across the countries’ shared borders, Mexico’s president said Tuesday there was no such agreement.

The U.S. Treasury sanctioned two Mexican cartels and seven cartel members on Thursday for drug trafficking, terrorism, and extorting farmers.

Ismael El Mayo Zambada, the accused co-founder of Mexico's Sinaloa cartel, is expected to plead guilty to U.S. drug trafficking charges, court records showed on Monday.

As a result of an investigation into an armed drug trafficking ring, 11 people were recently sentenced in Indianapolis Federal Court after hundreds of thousands of fentanyl pills and more than 15 kilograms of methamphetamine were trafficked into central Indiana.

Those charged include Juan Jose Farias Alvarez (“El Abuelo”); Alfonso Fernandez Magallon (“Poncho”); Luis Enrique Barragan Chavez (“Wicho / R5”); Edgar Orozco Cabadas (“El Kamoni”); and Nicolas Sierra Santana (“El Gordo”).

A man from Mexico was sentenced this week in federal court to almost five years in prison for trafficking approximately 58,000 fentanyl pills.