In pediatric critical care, the use of intravenous sedative infusions is a cornerstone of managing mechanically ventilated ...

Introduction: Continuous anesthetics are often required for the management of refractory status epilepticus. While essential to achieving seizure control, these agents carry significant adverse ...

The Association of Hospital and Administrative Pharmacists of Nigeria (AHAPN) has described the tragic death of Nkanu, the young son of Chimamanda Adichie, as a grave patient-safety failure rooted in ...

A coroner has called for more action to be taken to prevent further deaths after a teenager died while being sedated in hospital. Earlier this month, an inquest was held into the death of Antonio ...

A West Yorkshire Corner has issued a plea to prevent future deaths, following the death of a teenager who was sedated by "predators" for for "scientific insight". Wakefield Coroner's Court heard ...

Credit: Getty Images Researchers compared real-world performance of midazolam and propofol monotherapy at refractory status epilepticus onset. Compared with propofol, midazolam was associated with ...

Background: Propofol is a first-line sedative for critically ill adults receiving invasive mechanical ventilation (IMV). However, it can contribute to hemodynamic instability, especially in the ...

Objective: Propofol has been shown to produce a predictable and easily attainable level of sedation in postcardiac, head-injured, general trauma patients. The commencement of hemodiafiltration itself ...

Alpha2-adrenergic receptor agonists didn't get critically ill patients off the ventilator quicker than propofol in the head-to-head A2B trial. Median time from randomization to successful extubation ...