Atherosclerosis underlies most heart attacks and strokes and is now recognized as a chronic inflammatory disease rather than ...

Skeletal muscle is the largest metabolic organ in the body. It is composed of muscle fibers, blood vessels, nerves and connective tissue. In skeletal muscle, blood vessels are responsible for ...

Muscle relaxers help reduce muscle stiffness and pain from conditions like cerebral palsy and lower back pain. There are two main types of muscle relaxers: antispastics and antispasmodics. Muscle ...

A novel urine biomarker identified significant differences in muscle health between menopausal and nonmenopausal women, based on data from 113 individuals. Menopause is known to accelerate muscle loss ...

Danielle “Nellie” Bruns, an associate professor in the University of Wyoming’s Department of Zoology and Physiology, has received a five-year, $1.78 million research grant from the National Institutes ...

In this study, the authors developed an organoid system containing smooth muscle cells (SMCs) and interstitial cells of Cajal (ICCs; pacemaker cells), but few enteric neurons. This system generates ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. In this study, the ...

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...

Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed. Their findings, published in ...

This brief review describes recent advances in understanding metabolic control of vascular smooth muscle cells, highlighting the identification of KCNQ5 (K V 7.5 subfamily of voltage-gated K + ...

Ischemic cardiovascular disease remains one of the major causes of death and disability globally due to insufficient blood supply to vital organs and tissues. This vascular insufficiency poses a ...

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