Introduction: Cognitive and upper limb impairments are common following stroke. While transcutaneous electrical nerve stimulation, including transcutaneous vagus nerve stimulation (tVNS) and ...

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By removing the destructive SOD1 and TDP-43 proteins, the drug revitalized upper motor neurons, and in 2024 NU-9 received clinical trial approval to treat ALS from the US Food and Drug Administration.

A newly identified disorder, MINA syndrome, results from a mutation in the NAMPT protein that deprives motor neurons of energy, leading to severe movement problems. The discovery not only deepens ...

Motor neurons are some of the largest cells in the human body. In particular, upper neurons—extending from the cerebral cortex to the brain stem or spinal cord—average 60μm in diameter. 3,4 These ...

Highly degradative (dark) cells in the spinal cord were identified as motor neurons. [Kazuhide Asakawa, National Institute of Genetics] A defining feature of neurodegenerative disorders is selective ...

For years, researchers have been chasing a so-called silver bullet compound that could effectively treat anyone with amyotrophic lateral sclerosis (ALS). Hande Ozdinler, an associate professor of ...

1 Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, China 2 Department of Neurology, Affiliated Provincial Hospital of Hunan University of ...

In the beginning, not even Hynek Wichterle's postdoc thought his idea to slow the progression of amyotrophic lateral sclerosis (ALS) had a chance. "When Hynek proposed this, I thought it would never ...

Suzuki Motor USA, LLC (Suzuki) is recalling certain 2020-2025 DL 1050 and 2020, 2024 GSX-1000S motorcycles. The upper headlight beam may be too bright and exceed the maximum light output, which may ...

Johnathan Cooper-Knock receives funding from TargetALS, the ALS Association, the MND Association and the Lister Institute of Preventive Medicine. Pamela J. Shaw has received funding from The Motor ...

WINNETKA, Ill.--(BUSINESS WIRE)--Akava Therapeutics, Inc. is pleased to announce the publication in PNAS of results demonstrating benefits of its lead small molecule drug AKV9 for the treatment of ...