Crystalys Therapeutics has dosed the first patient with its once daily oral, URAT1 inhibitor dotinurad in its Phase II AMETHYST trial (NCT07535034), designed to assess dotinurad’s effectiveness in ...

Aarti Pharmalabs Ltd (BOM:543748) reported a 9% year-over-year increase in Q4 revenue, reaching Rs 580 crore. The Xanthine derivative segment achieved its highest-ever quarterly revenue, contributing ...

Crystalys Therapeutics Inc. ('Crystalys' or 'the Company'), a clinical-stage biopharmaceutical company addressing the significant unmet medical needs of people living with gout, today announced that ...

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Gout is a complex type of arthritis. It occurs due to high levels of uric acid in the blood, excess amounts of which can form sharp, painful crystals in the joints. Consuming foods with high ...

Cherries— especially tart cherries— are rich in antioxidants and anthocyanins that help in reducing inflammation and lowering uric acid levels naturally. A 2012 study titled 'Cherry consumption and ...

SINCE its clinical introduction in 1964, allopurinol (4-hydroxypyrazolo-[3,4-d]-pyrimidine) has been increasingly used for the treatment of hyperuricemia of gout, 1, 2 many neoplastic diseases and ...

Scientists detected all five nucleobases -- building blocks of DNA and RNA -- in samples returned from asteroid Bennu by NASA's OSIRIS-REx mission. Japanese collaborators detected all five nucleobases ...

IN 1954 Dent and Philpot 1 presented an account of xanthinuria observed in a four-year-old girl. She had only traces of uric acid in the blood and urine. Urinary excretion of purines consisted mainly ...

For gout, xanthine oxidase (XO) inhibitors are the choice for first-line urate-lowering therapy (ULT) according to the 2020 American College of Rheumatology Guideline for the Management of Gout, which ...

Hyperuricemia is a metabolic disorder caused by an imbalance in the production and excretion of uric acid (UA), and is considered to be a risk factor for gout, obesity, chronic kidney disease, and ...

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory ...